Burnley – unchanged from a 3-0 win over Southampton last weekend – looked dangerous whenever they had the chance to get a set-piece into the box.
And on one such occasion Bernd Leno was called on to make a point-blank save from Barnes, only for the forward to be flagged offside, before Matteo Guendouzi hooked the ball off the line following a goalmouth scramble.
Arsenal twice came close to a second as the half progressed, first Reiss Nelson broke in down the left before firing straight at Pope, the England goalkeeper then doing well to keep out a drive from Guendouzi soon after.
But it was Burnley who were level just before the interval as Barnes did well to collect a wayward Dwight McNeil shot inside the box and steer past Leno.
Nelson had the ball in the net for Arsenal but his effort on the stroke of half-time was ruled out for offside against Nacho Monreal, with a video assistant referee check confirming the decision was correct.
Unai Emery responded to the setback by introducing club-record signing Nicolas Pepe for the second half as Nelson made way for the Ivorian winger.
Aubameyang sent a curling effort inches wide and was then denied by Pope on the hour-mark after a fine pass from Pepe found the Gabon striker inside the box
Ceballos was the next to be frustrated as Pope pushed his strike away – but Aubameyang made sure he tucked away his next chance, firing home from the edge of the box to put the hosts back in front.
Sead Kolasinac replaced Lacazette, recently back from an ankle injury, and was given a rousing reception following recent off-field events.
